Hygiena 2012, 57(3):84-88

Contribution to the Assessment of the Health Risk of Occupational Exposure to Polycyclic Aromatic Hydrocarbons (PAHs)

Diana Ranná1, Lenka Borská2, Jindra Šmejkalová1, Lenka Kotingová1, Jan Kremláček2, Hana Tamchynová3
1 Univerzita Karlova v Praze, LF v Hradci Králové, Ústav hygieny a preventivního lékařství, Hradec Králové
2 Univerzita Karlova v Praze, LF v Hradci Králové, Ústav patologické fyziologie, Hradec Králové
3 Zdravotní ústav se sídlem v Hradci Králové, pracoviště Chrudim

The aim of our study was to contribute to the evaluation of health risk assessments of combined inhalation and dermal exposure to PAHs amongst road construction crews. Within the framework of evaluating inhalation and dermal exposure of persons there have been determined 15 selected PAHs. Assessments of genotoxic exposure (chromosomal aberrations of peripheral lymphocytes) were performed in the spring and autumn seasons with single blood samples in each case. Road construction crews were exposed to inhaled PAHs at levels significantly lower than those stipulated by work limits in the Czech Republic. According to the World Health Organization (WHO) assessment, the detected inhalation exposure to benzo(a)pyrene is also acceptable. Dermal exposure was low. We detected a significant increase in chromosomal aberrations of peripheral lymphocytes post season. This finding, however, did not exceed limit values. Genotoxic risk can be considered to be low.

Keywords: polycyclic aromatic hydrocarbons (PAHs) - exposure, genotoxic risks, occupational exposure

Received: October 2011; Accepted: January 30, 2012; Published: September 1, 2012  Show citation

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Ranná D, Borská L, Šmejkalová J, Kotingová L, Kremláček J, Tamchynová H. Contribution to the Assessment of the Health Risk of Occupational Exposure to Polycyclic Aromatic Hydrocarbons (PAHs). Hygiena. 2012;57(3):84-88.
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