Hygiena 2010, 55(2):54-57

The Risk of Generation of Carcinogenic Para-chloroaniline within Endodontic Therapy of Devitalised Teeth

Ján Kováč, Daniel Kováč
Klinika stomatológie a maxilofaciálnej chirurgie LFUK a OÚSA, Bratislava

The purpose of this article is to report on potential risk of formation of para-chloroaniline (PCA), a breakdown product of chlorhexidine (CHX) a toxic and carcinogenic compound. The generation of PCA is a potential consequence of the use of chlorhexidine which has been widely used as an antiseptic agent for routine dental plaque control and irrigation of root canals in endodontic treatment of devitalised, pulpless teeth, for reduction of microbiota.

Keywords: para-chloroaniline, PCA, 4-chloroaniline, chlorhexidine, breakdown product of chlorhexidine

Received: January 2010; Accepted: February 4, 2010; Published: June 1, 2010  Show citation

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Kováč J, Kováč D. The Risk of Generation of Carcinogenic Para-chloroaniline within Endodontic Therapy of Devitalised Teeth. Hygiena. 2010;55(2):54-57.
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